The Nonartemisinin Sesquiterpene Lactones Parthenin and Parthenolide Block Plasmodium falciparum Sexual Stage Transmission
نویسندگان
چکیده
منابع مشابه
Limited polymorphism in Plasmodium falciparum sexual-stage antigens.
In areas highly endemic for malaria, individuals are frequently found to be infected simultaneously with multiple Plasmodium falciparum clones. This raises the question of whether all parasite clones produce gametocytes equally or whether gametocytogenesis is suppressed in some clones. In order to assess this in epidemiological studies, polymorphic genes specifically expressed in gametocytes co...
متن کاملPhytochemical Review Profile of Sesquiterpene Lactone Parthenin
Parthenin (a sesquiterpene lactone) is a major constituent of parthenium hysterophorus –a noxious weed known for its environmental and health hazardous properties. . It is responsible for imparting the several properties to this weed such as allelpathy, autotoxicity and allergencity. Further, anticancerous, antiameobic and antimalarial properties of the weed are also credited to parthenin. The ...
متن کاملSesquiterpene Lactones from Achillea
The species of genus Achillea, particularly those belonging to the Achillea millefolium group have received a lot of attention so far, due to their use in traditional medicine. Among the numerous chemical compounds isolated from the A. millefolium species, the sesquiterpene lactones are usually one of the major constituents (Seaman, 1982). Continuing our chemotaxonomic examination of Bulgarian ...
متن کاملSesquiterpene lactones from Chrysolaena platensis.
A.L. Cabrera's treatment of Argentine Vernonias (Cabrera, 1944) included four members of his Section Lepidaploa, subsection Flexuosae, three of which were listed as occurring in Entre Rios Province (Cabrera, 1974). Two of these, V. cognata Less. and V. platensis (Spreng.) Less., were said to be closely related, di!ering from each other only in the number of #owers in the capitulum, diameter of ...
متن کاملSesquiterpene lactones from Elephantopus scaber
The ethanolic and acetone extracts of the whole plant of Elephantopus scaber were found to contain ethyl hexadecanoate, ethyl-9,12-octadecadienoate, ethyl-(Z)9-octadecenoate, ethyl octadecanoate, lupeol, stigmasterol, stigmasterol glucoside, deoxyelephantopin (1) and two new germacranolide sesquiterpene lactones named 17,19-dihydrodeoxyelephantopin (2) and iso-17,19-dihydrodeoxyelephantopin (3)...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2016
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.02002-15